Alkaline Phosphatase-Triggered Self-Assembly of Near-Infrared Nanoparticles for the Enhanced Photoacoustic Imaging of Tumors Nano Lett. 2018 Dec 12;18(12) :7749-7754. ... which self-assembled into the nanoparticles 1-NPs. The formation of 1-NPs induced a 6.4-fold enhancement of the 795 nm PA signal of 1P. In …
The rarity of efficient tools with spatiotemporal resolution and biocompatibility capabilities remains a major challenge for further progress and application of signaling manipulation. Herein, biomimetic conjugated oligomeric nanoparticles (CM-CONs) were developed to precisely modulate blood glucose homeostasis via the two …
Persistent luminous nanoparticles (PLNPs) have been capturing increasing attention in biomedical imaging because of their long-life emission and concomitant benefits (e.g., zero-autofluorescence background, high signal-to-noise ratio). Although there are quite some synthetic methodologies to synthesize PLNPs, those for constructing …
Near-infrared (NIR) fluorophores have attracted great attention due to their excellent optical and photothermal properties. Among them, a bone-targeted NIR fluorophore (named P800SO3) contains two phosphonate groups, which play important roles in binding with hydroxyapatite (HAP) as the main mineral component of bones. In …
With reduced photon scattering, minimal tissue absorption and negligible autofluorescence properties, near-infrared light (NIR 700–1700 nm) demonstrates better resolution, high …
Nucleus-targeting near-infrared nanoparticles based on TAT peptide-conjugated IR780 for photo-chemotherapy of breast cancer. Author links open overlay panel Guoyun Wan a 1, Yuanyuan Cheng a 1, ... IR780, a near-infrared (NIR) fluorescence dye that has potent anticancer efficacy of PTT and PDT, was firstly conjugated with TAT …
Xu's group developed a near-infrared light responsive nanoparticle for synergistic therapy. Cisplatin (CDDP) (a common anti-cancer drug) and indocyanine green (ICG) (as photosensitizer) were simultaneously encapsulated in the inner core of a nanocarrier formed by amphiphilic tellurium containing ABA triblock polymer (PEG 5000 …
Upconversion nanoparticles (UCNs) have the extraordinary ability to emit light with UV-visible wavelengths on illumination in the near IR region. This protocol describes the preparation of UCNs ...
The photophysical properties of nanoparticles were then studied. Results indicated that PDT-NP had a strong absorption peak centered at 604 nm. Moreover, there was strong fluorescence emission in the second NIR window (NIR II, 950–1700 nm) with a major peak centered at 1067 nm (Figure 1E). To verify the PDT effect of PDT-NP, 1,3 ...
DOI: 10.1002/adhm.202303593. Current nucleic acid delivery methods have not achieved efficient, non-toxic delivery of miRNAs with tumor-specific selectivity. In this study, a new delivery system based on light-inducible gold-silver-gold, core-shell-shell (CSS) nanoparticles is presented. This system delivers small nucleic acid ….
Boron dipyrromethene (BODIPY) is a class of important emerging fluorescent dyes. Due to their unique chemical and optical properties, near infrared (NIR)-emitting BODIPY dyes containing nanoparticles have recently been developed for a wide array of cutting-edge cancer optotheranostic applications.
Under the circumstance, broadly defined near-infrared (NIR) imaging region that spans NIR-I (700–900 nm) ... Long wavelength excitable near-infrared fluorescent nanoparticles with aggregation-induced emission characteristics for image-guided tumor resection. Chemical Science, 8 (2017), pp. 2782-2789.
Due to the unique properties of lanthanide-doped upconverting nanoparticles (UCNP) under near-infrared (NIR) light, the last decade has shown a …
Development of second near-infrared (NIR-II) nanoparticles (NPs) with high biocompatibility, low toxicity, and high singlet oxygen quantum yield (Φ Δ) to prevent tumor recurrence is highly desirable in molecular imaging and photodynamic/immune combination therapy.Here, theranostic photosensitizer BODIPY (BDP)-I-N-anti-PD-L1 …
Near-Infrared Laser-Excited Nanoparticles To Eradicate Multidrug-Resistant Bacteria and Promote Wound Healing ACS Appl Mater Interfaces. 2018 Jan 10;10(1):193-206. doi: 10.1021/acsami.7b15251. ... Taking the advantage of its strong near-infrared absorbance, photothermal treatment is also conducted with Tri-Ag, …
Abstract. Development of second near-infrared (NIR-II) nanoparticles (NPs) with high biocompatibility, low toxicity, and high singlet oxygen quantum yield (Φ Δ) to prevent tumor recurrence is highly …
Herein, we develop a polymer nanoplatform that integrates long-wavelength second near-infrared (NIR-II) photoacoustic imaging-based thrombosis detection and antithrombotic activity. We design and synthesize a semiconducting homopolymer with strong absorption in the NIR-II region and molecular motion that boosts photothermal …
Rare-earth doped nanoparticles (RENPs) are attracting increasing interest in materials science due to their optical, magnetic, and chemical properties. RENPs can emit and absorb radiation in the second biological window (NIR-II, 1000–1400 nm) making them ideal optical probes for photoluminescence (PL) in vivo imaging. Their narrow emission bands …
Near-infrared (NIR) light is well-suited for the optical imaging and wireless phototherapy of malignant diseases because of its deep tissue penetration, low autofluorescence, weak tissue scattering, and non-invasiveness. Rare earth nanoparticles (RENPs) are promising NIR-responsive materials, owing to their excellent physical and chemical ...
In contrast, Near-infrared (NIR) light possesses the minimum effect on human health due to its low phototoxicity [26], [27]. ... and the degradation of dyes and pollutants. Briefly, the platinum nanoparticles may also be anchored on the surfaces of other natural enzymes (e.g., oxidase, dehydrogenase, hydrolases, and cellulase) for …
A near infrared squaraine dye (SQ) is synthesized with high photostability and high photothermal conversion efficiency. • The dye SQ was encapsulated into …
The near-infrared (NIR) region of the spectrum is called the "therapeutic window" because NIR light can penetrate deeply into tissue. Therefore, NIR-sensitive materials are attractive for biomedical applications. Recently, upconverting nanoparticles (UCNPs) were used to construct NIR-sensitive materials. UCNPs convert NIR light to …
In addition, near-infrared surface plasmon resonance (SPR) microscopy has been used to detect the sequence-selective hybridization adsorption of single DNA-functionalized gold nanoparticles [77]. The accumulation of AuNPs onto a gold thin film functionalized with a complementary DNA surface was monitored.
This review discusses applications that have successfully demonstrated the utility of nanoparticles for NIR imaging, including NIR-emitting semiconductor quantum dots …
Extremely inefficient utilization of pesticides has prompted a study of low-cost, sustainable, and smart application systems. Herein, as a promising pesticide nanocarrier, hollow mesoporous organosilica nanoparticles (HMONs) were first synthesized by using inexpensive CaCO3 nanoparticles as the hollow templates. A redox/near-infrared light …
The Pt nanoparticles possess broadband near-infrared light absorption in the range from 650 to 1200 nm, therefore allowing for selecting different laser wavelengths for photothermal therapy. The as-prepared Pt nanoparticles exhibit remarkable photothermal conversion efficiencies under 809 and 980 nm laser irradiation. In vitro studies indicate ...
However, the efficiency of existing PDT drug molecules in the deep-tissue-penetrable near-infrared (NIR) region has been the major hurdle that has hindered further development and clinical usag … Enhancing Photodynamic Therapy through Resonance Energy Transfer Constructed Near-Infrared Photosensitized Nanoparticles
Lastly, derivatives of the amphiphilic near-infrared (NIR) dye cyanine, designated C11-PC (a cyanine dye having 11 carbon chains conjugated with phosphocholine) and C11-PEG 800 (a cyanine dye having 11 carbon chains conjugated with polyethylene glycol 800) [23], were used to construct the nanoparticle mass as …
Near infrared imaging has presented itself as a powerful diagnostic technique with potential to serve as a minimally invasive, nonionizing method for sensitive, deep tissue diagnostic imaging. This potential is further realized with the use of nanoparticle (NP)-based near infrared (NIR) contrast age …
Near-infrared (NIR) irradiation has shown great potential for clinical light therapy as well as for cosmetic purposes 1,2,3 and successfully been applied to photorejuvenation, photoprotection, and ...